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Understand Lipase

Lipase

Liver markers

What the test generally measures, and what to ask about it.

Longetic keeps every lab and record you’ve had organized and easy to find, so your own Lipase values sit together on one chart and you walk into your next appointment prepared.

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Updated Jul 13, 2026

What is Lipase?

A digestive enzyme, made mainly by the pancreas, that helps your body break down fats.

Lipase is an enzyme that helps digest dietary fats and is produced largely by the pancreas. A markedly high level can be associated with acute pancreatitis, and raised levels may also be associated with a blocked pancreatic duct, gallbladder or intestinal problems, or kidney disease. Low levels can sometimes be associated with lasting pancreas damage. Lipase is generally considered more accurate for diagnosing pancreatitis than amylase.

This glossary entry is for informational purposes only and is not a substitute for professional medical advice. Read our Terms of Use.

References

Clinical "Lipase Tests" MedlinePlus (NIH/NLM). medlineplus.gov/lab-tests/lipase-tests.
Clinical "Amylase Test" MedlinePlus (NIH/NLM). medlineplus.gov/lab-tests/amylase-test.

About our sources

Clinical / professional

Medical societies, specialty colleges, and professional associations whose consensus statements reflect clinical practice standards.

Peer-reviewed research

Original research articles and systematic reviews published in indexed journals and verified through PubMed or DOI.

History of updates

Published · Jul 13, 2026
First published; written and independently fact-checked against the cited sources.

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