Castelli Risk Index II
Here’s what it reflects — and what to do about it.
Longetic pulls together every lab and record you’ve had, follows how Castelli Risk Index II changes over time, and explains what’s shifting — so you walk into your next appointment prepared, with reminders for retests along the way.
What is Castelli Risk Index II?
A calculated ratio of bad (LDL) cholesterol to good (HDL) cholesterol.
This is a calculated value from a standard lipid panel: it divides your LDL by your HDL (LDL divided by HDL). A higher ratio means more artery-clogging cholesterol relative to the protective kind and can be associated with greater cardiovascular risk, a lower ratio can be associated with a healthier balance. Castelli Risk Index II is mathematically the same as the LDL/HDL ratio.
What to know about Castelli Risk Index II
Understanding Castelli Risk Index II means knowing what it reflects, what tends to move it, and the signs that suggest it’s worth a closer look — so you can bring the right questions to your next appointment.
This glossary entry is for informational purposes only and is not a substitute for professional medical advice. Read our Medical Disclaimer.
References
About our sources
Official sources
Government health agencies, national institutes, and intergovernmental bodies whose guidelines carry regulatory or policy weight.
Clinical / professional
Medical societies, specialty colleges, and professional associations whose consensus statements reflect clinical practice standards.
Peer-reviewed research
Original research articles and systematic reviews published in indexed journals and verified through PubMed or DOI.