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ApoB/ApoA1 Ratio

Heart & circulation markers

What the test generally measures, and what to ask about it.

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Updated Jul 13, 2026

What is ApoB/ApoA1 Ratio?

A calculated ratio comparing the main protein on bad cholesterol particles (ApoB) to the main protein on good cholesterol particles (ApoA1).

This is a calculated value, not a separate blood draw: it divides your apolipoprotein B (one per atherogenic particle such as LDL) by your apolipoprotein A1 (the main protein in HDL). A higher ratio means more cholesterol-carrying particles relative to protective ones and can be associated with greater cardiovascular risk, a lower ratio can be associated with a more favorable balance. It comes from an extended apolipoprotein panel, not a routine lipid screen.

This glossary entry is for informational purposes only and is not a substitute for professional medical advice. Read our Terms of Use.

References

Official source "High apolipoprotein B, low apolipoprotein A-I, and prediction of fatal myocardial infarction (AMORIS)" PubMed. pubmed.ncbi.nlm.nih.gov/11755609.

About our sources

Clinical / professional

Medical societies, specialty colleges, and professional associations whose consensus statements reflect clinical practice standards.

Peer-reviewed research

Original research articles and systematic reviews published in indexed journals and verified through PubMed or DOI.

History of updates

Published · Jul 13, 2026
First published, calculated index, formula + sources independently fact-checked.

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