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Understand Total Triiodothyronine (Total T3)

Total Triiodothyronine (Total T3)

Hormone markers

What the test generally measures, and what to ask about it.

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Updated Jul 13, 2026

What is Total Triiodothyronine (Total T3)?

Measures all of the active thyroid hormone triiodothyronine in your blood, both the free portion and the part bound to proteins.

Triiodothyronine, or T3, is one of the main thyroid hormones that set the pace of your metabolism, and the total T3 test measures the free and protein-bound amounts together. Higher levels can be associated with an overactive thyroid, while lower levels can be associated with an underactive thyroid or with non-thyroid illness. T3 is usually checked as part of a broader thyroid panel with TSH and T4 rather than on its own.

This glossary entry is for informational purposes only and is not a substitute for professional medical advice. Read our Terms of Use.

References

Clinical "Triiodothyronine (T3) Tests" MedlinePlus (NIH/NLM). medlineplus.gov/lab-tests/triiodothyronine-t3-tests.
"Thyroid Function Tests" American Thyroid Association. www.thyroid.org/thyroid-function-tests.

About our sources

Clinical / professional

Medical societies, specialty colleges, and professional associations whose consensus statements reflect clinical practice standards.

Peer-reviewed research

Original research articles and systematic reviews published in indexed journals and verified through PubMed or DOI.

History of updates

Published · Jul 13, 2026
First published, written and independently fact-checked against the cited sources.

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