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Understand Monocyte-to-HDL Ratio (MHR)

Monocyte-to-HDL Ratio (MHR)

Immunity & allergy markers

What the test generally measures, and what to ask about it.

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Updated Jul 13, 2026

What is Monocyte-to-HDL Ratio (MHR)?

A calculated ratio combining an inflammatory white-blood-cell count (monocytes) with good (HDL) cholesterol.

This is a calculated value combining two routine results: it divides your monocyte count (from a CBC) by your HDL cholesterol (from a lipid panel). Because monocytes drive inflammation and HDL helps counter it, a higher MHR can be associated with more inflammation and, in research, cardiovascular and metabolic risk, a lower value can be associated with a more favorable balance. It is a general marker, not a diagnosis.

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References

Official source "Monocyte to HDL ratio as a marker of resistant hypertension (Gembillo 2021)" PubMed. pubmed.ncbi.nlm.nih.gov/34109496.

About our sources

Clinical / professional

Medical societies, specialty colleges, and professional associations whose consensus statements reflect clinical practice standards.

Peer-reviewed research

Original research articles and systematic reviews published in indexed journals and verified through PubMed or DOI.

History of updates

Published · Jul 13, 2026
First published, calculated index, formula + sources independently fact-checked.

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