Lp-PLA2 (Lipoprotein-Associated Phospholipase A2)
Here’s what it reflects — and what to do about it.
Longetic pulls together every lab and record you’ve had, follows how Lp-PLA2 (Lipoprotein-Associated Phospholipase A2) changes over time, and explains what’s shifting — so you walk into your next appointment prepared, with reminders for retests along the way.
What is Lp-PLA2 (Lipoprotein-Associated Phospholipase A2)?
An enzyme carried mostly on LDL that is linked to inflammation inside artery walls.
Lp-PLA2 is an enzyme that travels mainly with LDL cholesterol and is tied to the inflammation that can build up within artery walls. Higher levels have been associated in research with a greater risk of plaque-related cardiovascular events, which is why it is sometimes used as an add-on to help refine risk in people who are already at intermediate risk. It is an advanced, optional marker rather than part of a routine cardiovascular panel.
What to know about Lp-PLA2 (Lipoprotein-Associated Phospholipase A2)
Understanding Lp-PLA2 (Lipoprotein-Associated Phospholipase A2) means knowing what it reflects, what tends to move it, and the signs that suggest it’s worth a closer look — so you can bring the right questions to your next appointment.
This glossary entry is for informational purposes only and is not a substitute for professional medical advice. Read our Medical Disclaimer.
References
About our sources
Official sources
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Clinical / professional
Medical societies, specialty colleges, and professional associations whose consensus statements reflect clinical practice standards.
Peer-reviewed research
Original research articles and systematic reviews published in indexed journals and verified through PubMed or DOI.