Understand DHEA-Sulfate (DHEA-S)

DHEA-Sulfate (DHEA-S)

Here’s what it reflects — and what to do about it.

Longetic pulls together every lab and record you’ve had, follows how DHEA-Sulfate (DHEA-S) changes over time, and explains what’s shifting — so you walk into your next appointment prepared, with reminders for retests along the way.

Summarize with AI
9:41
Biomarker snapshot
Vitamin D
52ng/mL
Normal
LDL
165mg/dL
High
Glucose
92mg/dL
Normal
Vitamin B12
296pg/mL
Low
Focus zones
Sleep & Recovery
It reflects how your daily choices shape your long-term health
Lifestyle Habits
It reflects how your daily choices shape your long-term health
Stress Level
It reflects how your daily choices shape your long-term health
Vitality
It reflects how your daily choices shape your long-term health
Journey
Discovery
Longevity
Profile
Updated Jul 13, 2026

What is DHEA-Sulfate (DHEA-S)?

An androgen (a male-type sex hormone) made mostly by the adrenal glands, present in both men and women.

DHEA-S is a steroid hormone produced mainly by the adrenal glands and serves as a building block for testosterone and estrogen; levels peak in young adulthood and decline with age. Because it comes largely from the adrenals, it is often used to check how those glands are working. Higher DHEA-S can be associated with adrenal conditions such as congenital adrenal hyperplasia, an adrenal tumor, or PCOS in women; lower levels can be associated with Addison disease or a pituitary problem. Results are interpreted with symptoms, age, sex, and other hormone tests.

What to know about DHEA-Sulfate (DHEA-S)

Understanding DHEA-Sulfate (DHEA-S) means knowing what it reflects, what tends to move it, and the signs that suggest it’s worth a closer look — so you can bring the right questions to your next appointment.

This glossary entry is for informational purposes only and is not a substitute for professional medical advice. Read our Medical Disclaimer.

References

Clinical "DHEA Sulfate Test" MedlinePlus (NIH/NLM). medlineplus.gov/lab-tests/dhea-sulfate-test.

About our sources

Clinical / professional

Medical societies, specialty colleges, and professional associations whose consensus statements reflect clinical practice standards.

Peer-reviewed research

Original research articles and systematic reviews published in indexed journals and verified through PubMed or DOI.

History of updates

Published · Jul 13, 2026
First published; written and independently fact-checked against the cited sources.

Track your DHEA-Sulfate (DHEA-S) over time with Longetic

Upload a lab, and Longetic reads it, explains it, and reminds you when it's time to re-check — so nothing slips between visits.