Castelli Risk Index I
Here’s what it reflects — and what to do about it.
Longetic pulls together every lab and record you’ve had, follows how Castelli Risk Index I changes over time, and explains what’s shifting — so you walk into your next appointment prepared, with reminders for retests along the way.
What is Castelli Risk Index I?
A calculated ratio of total cholesterol to good (HDL) cholesterol, long used as a snapshot of cardiovascular risk.
This is a calculated value from a routine lipid panel, not a separate test: it divides your total cholesterol by your HDL (Total Cholesterol divided by HDL). A higher ratio means more overall cholesterol relative to the protective kind and can be associated with higher cardiovascular risk, a lower ratio can be associated with a more favorable balance. It is a general indicator, not a diagnosis.
What to know about Castelli Risk Index I
Understanding Castelli Risk Index I means knowing what it reflects, what tends to move it, and the signs that suggest it’s worth a closer look — so you can bring the right questions to your next appointment.
This glossary entry is for informational purposes only and is not a substitute for professional medical advice. Read our Medical Disclaimer.
References
About our sources
Official sources
Government health agencies, national institutes, and intergovernmental bodies whose guidelines carry regulatory or policy weight.
Clinical / professional
Medical societies, specialty colleges, and professional associations whose consensus statements reflect clinical practice standards.
Peer-reviewed research
Original research articles and systematic reviews published in indexed journals and verified through PubMed or DOI.